Substance Admin Substitution

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Lvl- Typ	Concept Code Head Code-defined Value Set	Print Name	Definition, Properties, Relationships
substanceAdminSubstitution [2.16.840.1.113883.5.1070] Description: Identifies what sort of change is permitted or has occurred between the therapy that was ordered and the therapy that was/will be provided.
0-A	_ActSubstanceAdminSubstitutionCode v:ActSubstanceAdminSubstitutionCode	ActSubstanceAdminSubstitutionCode	Definition: Description: Substitution occurred or is permitted with another product that may potentially have different ingredients, but having the same biological and therapeutic effects. Concept Relationships: Generalizes (derived): E F N
1-S	. E	equivalent	Definition: Description: Substitution occurred or is permitted with another bioequivalent and therapeutically equivalent product. Concept Relationships: Specializes: _ActSubstanceAdminSubstitutionCode Generalizes (derived): EC TE
2-S	. . EC	equivalent composition	Definition: Description: Substitution occurred or is permitted with another product that is a: pharmaceutical alternative containing the same active ingredient but is formulated with different salt, ester pharmaceutical equivalent that has the same active ingredient, strength, dosage form and route of administration Examples: Pharmaceutical alternative: Erythromycin Ethylsuccinate for Erythromycin Stearate Pharmaceutical equivalent: Lisonpril for Zestril Concept Relationships: Specializes: E Generalizes (derived): BC G
3-L	. . . BC	brand composition	Definition: Description: Substitution occurred or is permitted between equivalent Brands but not Generics Examples: Zestril for Prinivil Coumadin for Jantoven Concept Relationships: Specializes: EC
3-L	. . . G . . . v:SubstanceAdminGenericSubstitution	generic composition	Definition: Description: Substitution occurred or is permitted between equivalent Generics but not Brands Examples: Lisnopril (Lupin Corp) for Lisnopril (Wockhardt Corp) Concept Relationships: Specializes: EC
2-S	. . TE	therapeutic alternative	Definition: Description: Substitution occurred or is permitted with another product having the same therapeutic objective and safety profile. Examples: ranitidine for Tagamet Concept Relationships: Specializes: E Generalizes (derived): TB TG
3-L	. . . TB	therapeutic brand	Definition: Description: Substitution occurred or is permitted between therapeutically equivalent Brands but not Generics Examples: Zantac for Tagamet Concept Relationships: Specializes: TE
3-L	. . . TG	therapeutic generic	Definition: Description: Substitution occurred or is permitted between therapeutically equivalent Generics but not Brands Examples: Ranitidine for cimetidine Concept Relationships: Specializes: TE
1-L	. F	formulary	Definition: Description: This substitution was performed or is permitted based on formulary guidelines. Concept Relationships: Specializes: _ActSubstanceAdminSubstitutionCode
1-L	. N	none	Definition: No substitution occurred or is permitted. Concept Relationships: Specializes: _ActSubstanceAdminSubstitutionCode

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Last Published: 20120831 10:21 AM

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